GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases expression | EXP | | 6480464 | CTD | Aflatoxin B1 results in increased expression of CASP3 mRNA | PMID:27288928 PMID:33354967 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA] | PMID:27288928 | Casp3 | decreases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in decreased expression of CASP3 protein | PMID:22743290 | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Aflatoxin B1 results in increased activity of CASP3 protein | PMID:35304092 | Casp3 | increases cleavage | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Aflatoxin B1 results in increased cleavage of CASP3 protein | PMID:33421461 PMID:34396909 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in increased cleavage of CASP3 protein | PMID:22743290 | Casp3 | increases expression | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Aflatoxin B1 results in increased expression of CASP3 mRNA; Aflatoxin B1 results in increased expression of CASP3 protein | PMID:19770486 PMID:25445755 PMID:28789997 PMID:30126036 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Aflatoxin B1 results in increased expression of CASP3 mRNA | PMID:27017951 PMID:30668976 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; PRKN protein affects the reaction [Aflatoxin B1 results in increased activity of CASP3 protein] | PMID:25445755 PMID:35304092 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; CYP2A13 protein promotes the reaction [Aflatoxin B1 results in increased cleavage of CASP3 protein]; gluconic acid promotes the reaction [Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]]; Methoxsalen inhibits the reaction [Aflatoxin B1 results in increased cleavage of CASP3 protein]; Nicotine inhibits the reaction [Aflatoxin B1 results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA] | PMID:22743290 PMID:27017951 PMID:30668976 | |
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