GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347922
Species: Homo sapiens
RGD Object: Gene
Symbol: PCK1
Name: phosphoenolpyruvate carboxykinase 1 (soluble)
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
CasRN: 1162-65-8
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:110626480464CTDAflatoxin B1 results in decreased expression of PCK1 mRNA

PMID:19770486
affects expressionEXP 6480464CTDAflatoxin B1 affects the expression of PCK1 protein

PMID:20106945
decreases expressionEXP 6480464CTDAflatoxin B1 results in decreased expression of PCK1 mRNA

PMID:22100608
increases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of PCK1 mRNA

PMID:22100608
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