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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3771 Species: Rattus norvegicus RGD Object: Gene Symbol: Stat1 Name: signal transducer and activator of transcription 1

Acc ID: CHEBI:23995 Term: N-ethyl-N-nitrosourea Definition: A urea compound having ethyl and nitroso substituents in the 1-position. CasRN: 759-73-9 Chemical ID: MESH:D005038

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases mutagenesis	ISO	RGD:732185	6480464	CTD	Ethylnitrosourea results in increased mutagenesis of STAT1 gene	PMID:16688530 PMID:16724327
increases mutagenesis	ISO	RGD:732185	6480464	CTD	Ethylnitrosourea results in increased mutagenesis of STAT1 gene	PMID:16724327 PMID:16688530