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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305051 Species: Rattus norvegicus RGD Object: Gene Symbol: Aen Name: apoptosis enhancing nuclease

Acc ID: CHEBI:23995 Term: N-ethyl-N-nitrosourea Definition: A urea compound having ethyl and nitroso substituents in the 1-position. CasRN: 759-73-9 Chemical ID: MESH:D005038

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1551717	6480464	CTD	Ethylnitrosourea results in increased expression of AEN mRNA	PMID:19100860