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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:2394
Term: acetochlor
Definition: A monocarboxylic acid amide that is N-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively.
Chemical ID: MESH:C043377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases activityISOABCB1 (Homo sapiens)6480464CTDacetochlor results in increased activity of ABCB1 proteinPMID:18433974
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDABCB1 protein affects the reaction [acetochlor results in increased susceptibility to Paclitaxel]PMID:18433974
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