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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:23414
Term: copper(II) sulfate
Definition: A metal sulfate compound having copper(2+) as the metal ion.
Chemical ID: MESH:D019327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1affects expressionISOCYP1A1 (Homo sapiens)6480464CTDCopper Sulfate affects the expression of CYP1A1 mRNAPMID:19549813
Cyp1a1increases expressionISOCYP1A1 (Homo sapiens)6480464CTDCopper Sulfate results in increased expression of CYP1A1 mRNAPMID:16283523
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTDCopper Sulfate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]PMID:17889500
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