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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2180
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp7b
Name: ATPase copper transporting beta
Acc ID: CHEBI:23414
Term: copper(II) sulfate
Definition: A metal sulfate compound having copper(2+) as the metal ion.
Chemical ID: MESH:D019327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp7bdecreases expressionISOATP7B (Homo sapiens)6480464CTDCopper Sulfate results in decreased expression of ATP7B mRNAPMID:19549813
Atp7bdecreases response to substanceISOATP7B (Homo sapiens)6480464CTDATP7B protein results in decreased susceptibility to Copper SulfatePMID:10728692
Atp7bincreases expressionISOATP7B (Homo sapiens)6480464CTDCopper Sulfate results in increased expression of ATP7B mRNA; Copper Sulfate results in increased expression of ATP7B proteinPMID:24815816
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