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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:23115
Term: chlorohydrocarbon
Definition: A compound derived from a hydrocarbon by replacing at least one hydrogen atom with a chlorine atom.
Chemical ID: MESH:D006843
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases phosphorylationISOAKT1 (Homo sapiens)6480464CTDHydrocarbons, Chlorinated results in increased phosphorylation of AKT1 proteinPMID:14757120
Akt1multiple interactionsISOAKT1 (Homo sapiens)6480464CTDwortmannin inhibits the reaction [Hydrocarbons, Chlorinated results in increased phosphorylation of AKT1 protein]PMID:14757120
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