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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552280 Species: Mus musculus RGD Object: Gene Symbol: Nefl Name: neurofilament, light polypeptide

Acc ID: CHEBI:23012 Term: carbon disulfide Definition: An organosulfur compound that has formula CS2. CasRN: 75-15-0 Chemical ID: MESH:D002246

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:621458	6480464	CTD	Carbon Disulfide results in decreased expression of NEFL protein	PMID:16474999 PMID:17120161
increases expression	ISO	RGD:621458	6480464	CTD	Carbon Disulfide results in increased expression of NEFL mRNA	PMID:17120161
decreases expression	ISO	RGD:621458	6480464	CTD	Carbon Disulfide results in decreased expression of NEFL protein	PMID:17120161 PMID:16474999
increases expression	ISO	RGD:621458	6480464	CTD	Carbon Disulfide results in increased expression of NEFL protein	PMID:19165470
increases expression	ISO	RGD:621458	6480464	CTD	Carbon Disulfide results in increased expression of NEFL mRNA	PMID:17120161 PMID:19165470