GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lep | affects expression | EXP | | 6480464 | CTD | Calcium affects the expression of LEP mRNA | PMID:15913539 | Lep | affects secretion | EXP | | 6480464 | CTD | Calcium deficiency affects the secretion of LEP protein | PMID:10780946 | Lep | multiple interactions | EXP | | 6480464 | CTD | Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein] | PMID:10780946 | Lep | affects abundance | ISO | Lep (Mus musculus) | 6480464 | CTD | LEP protein affects the abundance of Calcium | PMID:16380530 | Lep | decreases abundance | ISO | Lep (Mus musculus) | 6480464 | CTD | LEP protein results in decreased abundance of Calcium | PMID:14657008 | Lep | increases transport | ISO | Lep (Mus musculus) | 6480464 | CTD | LEP protein results in increased transport of Calcium | PMID:20107083 | Lep | multiple interactions | ISO | Lep (Mus musculus) | 6480464 | CTD | 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium] | PMID:16380530 PMID:20107083 | | ||||||||||||||||||||||
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