GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp2 | affects expression | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | Cadmium affects the expression of MMP2 mRNA | PMID:31154059 | Mmp2 | increases expression | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased expression of MMP2 mRNA; Cadmium results in increased expression of MMP2 protein | PMID:22884995 PMID:33559965 | Mmp2 | multiple interactions | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP2 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MMP2 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP2 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein; Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]; ESR1 protein alternative form affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP2 protein]; GPER1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP2 protein]; Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]; PKM protein affects the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]] | PMID:29741670 PMID:31468104 PMID:34481905 PMID:34687772 PMID:36336208 | | ||||||||||||||||||||||
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