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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2559
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Epo
Name: erythropoietin
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epomultiple interactionsISOEPO (Homo sapiens)6480464CTDCadmium inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EPO promoter]]; Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]PMID:10866824
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