GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Alpl | decreases activity | EXP | | 6480464 | CTD | Cadmium results in decreased activity of ALPL protein | PMID:26214600 | Alpl | multiple interactions | EXP | | 6480464 | CTD | Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein]; zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein] | PMID:26214600 | Alpl | decreases expression | ISO | ALPL (Homo sapiens) | 6480464 | CTD | Cadmium results in decreased expression of ALPL mRNA | PMID:20570719 | Alpl | multiple interactions | ISO | ALPL (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ALPL mRNA | PMID:32522577 | Alpl | multiple interactions | ISO | Alpl (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ALPL mRNA | PMID:37325564 | | ||||||||||||||||||||||
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