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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2165 Species: Rattus norvegicus RGD Object: Gene Symbol: Atf3 Name: activating transcription factor 3

Acc ID: CHEBI:22584 Term: antimycin A Definition: A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. CasRN: 1397-94-0 Chemical ID: MESH:D000968

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:10198	6480464	CTD	Antimycin A results in increased expression of ATF3 mRNA	PMID:19304788