• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889 Species: Rattus norvegicus RGD Object: Gene Symbol: Rela Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Acc ID: CHEBI:20993 Term: aldehydo-D-glucosamine Definition: The open-chain form of D-glucosamine. CasRN: 3416-24-8 Chemical ID: MESH:D005944

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]	PMID:18080321
multiple interactions	ISO	RGD:1352761	6480464	CTD	Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]	PMID:19020780
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]	PMID:18036590
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]	PMID:19375915
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]	PMID:12681956
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]	PMID:16431966
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]	PMID:17238806 PMID:18340449 PMID:16822504
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]	PMID:17498959
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]	PMID:16431966 PMID:17238806
increases localization	ISO	RGD:1352761	6480464	CTD	Glucosamine results in increased localization of RELA protein	PMID:20307528
multiple interactions	ISO	RGD:1551095	6480464	CTD	Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]	PMID:18205790
multiple interactions	ISO	RGD:1551095	6480464	CTD	Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]	PMID:18786831
multiple interactions	ISO	RGD:1551095	6480464	CTD	Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]] Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA] Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]	PMID:20737476
decreases activity	EXP		6480464	CTD	Glucosamine results in decreased activity of RELA protein	PMID:20737476
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]	PMID:16822504 PMID:17238806 PMID:18340449
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]	PMID:17238806 PMID:16431966
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]	PMID:18340449 PMID:16822504 PMID:17238806
multiple interactions	ISO	RGD:1352761	6480464	CTD	Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]	PMID:16822504 PMID:18340449 PMID:17238806