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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319854 Species: Homo sapiens RGD Object: Gene Symbol: SOX4 Name: SRY (sex determining region Y)-box 4

Acc ID: CHEBI:20993 Term: aldehydo-D-glucosamine Definition: The open-chain form of D-glucosamine. CasRN: 3416-24-8 Chemical ID: MESH:D005944

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1309488	6480464	CTD	Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]	PMID:17109745
decreases expression	ISO	RGD:1309488	6480464	CTD	Glucosamine results in decreased expression of SOX4 mRNA	PMID:17109745