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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Comt
Name: catechol-O-methyltransferase
Acc ID: CHEBI:19868
Term: 3',4'-dihydroxyacetophenone
Definition: A dihydroxyacetophenone that is acetophenone carrying hydroxy groups at positions 3' and 4'.
Chemical ID: MESH:C032940
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Comtincreases methylationISOCOMT (Homo sapiens)6480464CTDCOMT protein results in increased methylation of 3,4-dihydroxyacetophenonePMID:11160877
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