GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Alox5 | increases expression | ISO | ALOX5 (Homo sapiens) | 6480464 | CTD | Nicotine results in increased expression of ALOX5 mRNA; Nicotine results in increased expression of ALOX5 protein | PMID:14569062 PMID:20061081 | Alox5 | multiple interactions | ISO | ALOX5 (Homo sapiens) | 6480464 | CTD | [RTKI cpd co-treated with AG 1879] inhibits the reaction [Nicotine results in increased expression of ALOX5 protein]; AG 1879 inhibits the reaction [Nicotine results in increased expression of ALOX5 protein]; MK-886 inhibits the reaction [Nicotine results in increased expression of ALOX5 protein]; RTKI cpd inhibits the reaction [Nicotine results in increased expression of ALOX5 protein]; U 0126 inhibits the reaction [Nicotine results in increased expression of ALOX5 mRNA] | PMID:14569062 PMID:20061081 | |
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