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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:18721
Term: 3-chloropropane-1,2-diol
Definition: A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.
Chemical ID: MESH:D000517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases expressionEXP 6480464CTDalpha-Chlorohydrin results in decreased expression of ALDH1A1 mRNAPMID:35063618
Aldh1a1increases expressionEXP 6480464CTDalpha-Chlorohydrin results in increased expression of ALDH1A1 mRNA; alpha-Chlorohydrin results in increased expression of ALDH1A1 proteinPMID:26072098 PMID:28522335
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