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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lepr
Name: leptin receptor
Acc ID: CHEBI:18421
Term: superoxide
Definition: An oxygen radical that has formula O2.
Chemical ID: MESH:D013481
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Leprincreases abundanceISOLepr (Mus musculus)6480464CTDLEPR gene mutant form results in increased abundance of SuperoxidesPMID:19478208
Leprmultiple interactionsISOLepr (Mus musculus)6480464CTDacetovanillone inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides]; resveratrol inhibits the reaction [LEPR gene mutant form results in increased abundance of Superoxides]PMID:19478208
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