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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:18357
Term: (R)-noradrenaline
Definition: The R-enantiomer of noradrenaline.
Chemical ID: MESH:D009638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9increases activityEXP 6480464CTDNorepinephrine results in increased activity of MMP9 proteinPMID:16864425
Mmp9increases expressionEXP 6480464CTDNorepinephrine results in increased expression of MMP9 mRNAPMID:16864425
Mmp9multiple interactionsEXP 6480464CTDtrans-sodium crocetinate inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]PMID:16864425
Mmp9increases activityISOMMP9 (Homo sapiens)6480464CTDNorepinephrine results in increased activity of MMP9 proteinPMID:24929186
Mmp9increases expressionISOMMP9 (Homo sapiens)6480464CTDNorepinephrine results in increased expression of MMP9 mRNAPMID:24929186
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; Propranolol inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; SR 11302 inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; tanshinone inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]PMID:24929186
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