GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | decreases expression | EXP | | 6480464 | CTD | Norepinephrine results in decreased expression of SOD2 protein | PMID:19168439 | Sod2 | multiple interactions | EXP | | 6480464 | CTD | SHC1 protein affects the reaction [Norepinephrine results in decreased expression of SOD2 protein] | PMID:19168439 | Sod2 | increases expression | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Norepinephrine results in increased expression of SOD2 mRNA | PMID:23114885 | Sod2 | multiple interactions | ISO | SOD2 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; NFKB1 mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Norepinephrine promotes the reaction [[NFKB1 protein binds to RELA protein] which binds to SOD2 promoter]; prolinedithiocarbamate inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA] | PMID:23114885 | |
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