GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | Kynurenic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; Kynurenic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; methyl 5-((tert-butylcarbamothioylhydrazinylidene)methyl)-1-(2,4-difluorophenyl)pyrazole-4-carboxylate inhibits the reaction [Kynurenic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]] | PMID:35123988 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [Kynurenic Acid co-treated with IL1B protein] results in increased expression of CYP1A1 mRNA; AHR protein affects the reaction [[Kynurenic Acid co-treated with IL1B protein] results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [[Kynurenic Acid co-treated with IL1B protein] results in increased expression of IL6 mRNA]; IL1B protein promotes the reaction [Kynurenic Acid results in increased expression of IL6 mRNA] | PMID:20106948 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |