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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70884 Species: Rattus norvegicus RGD Object: Gene Symbol: Eif2ak3 Name: eukaryotic translation initiation factor 2 alpha kinase 3

Acc ID: CHEBI:18320 Term: 1,4-dithiothreitol Definition: The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. CasRN: 3483-12-3 Chemical ID: MESH:D004229

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Dithiothreitol results in increased phosphorylation of and results in increased activity of EIF2AK3 protein	PMID:12486162