GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Histamine results in increased phosphorylation of MAPK1 protein | PMID:30310171 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Histamine results in increased phosphorylation of MAPK1 protein | PMID:17656145 PMID:21179406 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | [Histamine binds to and results in increased activity of HRH4 protein] which results in increased phosphorylation of MAPK1 protein; Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK1 protein]; Histamine results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [Histamine results in increased phosphorylation of MAPK1 protein]; Pyrilamine inhibits the reaction [Histamine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; RTKI cpd inhibits the reaction [Histamine results in increased phosphorylation of MAPK1 protein] | PMID:11181941 PMID:16009787 PMID:17656145 PMID:21179406 | | ||||||||||||||||||||||
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