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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3694
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc18a2
Name: solute carrier family 18 member A2
Acc ID: CHEBI:18295
Term: histamine
Definition: A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.
Chemical ID: MESH:D006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc18a2increases secretionEXP 6480464CTDSLC18A2 protein results in increased secretion of HistaminePMID:14642791
Slc18a2multiple interactionsEXP 6480464CTDRabeprazole promotes the reaction [SLC18A2 protein results in increased secretion of Histamine]PMID:14642791
Slc18a2affects bindingISOSLC18A2 (Homo sapiens)6480464CTDHistamine binds to SLC18A2 proteinPMID:7912402
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