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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735440 Species: Homo sapiens RGD Object: Gene Symbol: NFKBIA Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Acc ID: CHEBI:18291 Term: manganese atom Definition: A manganese group element atom that has formula Mn. CasRN: 7439-96-5 Chemical ID: MESH:D008345

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:3171	6480464	CTD	Manganese promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased degradation of NFKBIA protein]	PMID:16488514
multiple interactions	ISO	RGD:3171	6480464	CTD	MAP3K14 protein affects the reaction [Manganese promotes the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]	PMID:15010209