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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312055 Species: Mus musculus RGD Object: Gene Symbol: Arhgef4 Name: Rho guanine nucleotide exchange factor (GEF) 4

Acc ID: CHEBI:18291 Term: manganese atom Definition: A manganese group element atom that has formula Mn. CasRN: 7439-96-5 Chemical ID: MESH:D008345

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1312054	6480464	CTD	Manganese results in increased expression of ARHGEF4 mRNA	PMID:17175027