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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2834
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Acc ID: CHEBI:18009
Term: NADP(+)
Definition: A NAD(P)(+) that has formula C21H29N7O17P3.
Chemical ID: MESH:D009249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd11b1increases oxidationEXP 6480464CTDHSD11B1 protein results in increased oxidation of NADPPMID:26859423
Hsd11b1increases reductionEXP 6480464CTDHSD11B1 protein results in increased reduction of NADPPMID:26859423
Hsd11b1multiple interactionsEXP 6480464CTDZiram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP]PMID:26859423
Hsd11b1increases oxidationISOHSD11B1 (Homo sapiens)6480464CTDHSD11B1 protein results in increased oxidation of NADPPMID:26859423
Hsd11b1increases reductionISOHSD11B1 (Homo sapiens)6480464CTDHSD11B1 protein results in increased reduction of NADPPMID:26859423
Hsd11b1multiple interactionsISOHSD11B1 (Homo sapiens)6480464CTDNADP binds to and results in increased activity of HSD11B1 proteinPMID:25526675
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