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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71032
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Folr1
Name: folate receptor alpha
Acc ID: CHEBI:17967
Term: urethane
Definition: A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.
Chemical ID: MESH:D014520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Folr1increases expressionISOFolr1 (Mus musculus)6480464CTDUrethane results in increased expression of FOLR1 mRNAPMID:12400877
Folr1multiple interactionsISOFolr1 (Mus musculus)6480464CTD[Urethane co-treated with Freund's Adjuvant] results in increased expression of FOLR1 mRNA; Freund's Adjuvant promotes the reaction [Urethane results in decreased expression of FOLR1 mRNA]PMID:12400877 PMID:12810352
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