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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708425
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Havcr1
Name: hepatitis A virus cellular receptor 1
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Havcr1affects expressionEXP 6480464CTDGentamicins affects the expression of HAVCR1 mRNAPMID:20623750
Havcr1increases expressionEXP 6480464CTDGentamicins results in increased expression of HAVCR1 mRNA; Gentamicins results in increased expression of HAVCR1 proteinPMID:17636248 PMID:17934191 PMID:18289764 PMID:18441258 PMID:19349640 PMID:19535489 PMID:20118187 PMID:20660082 PMID:20849911 PMID:22061828 PMID:23142791 PMID:26779593 PMID:29126144 PMID:34350654
Havcr1increases secretionEXP 6480464CTDGentamicins results in increased secretion of HAVCR1 proteinPMID:20816719
Havcr1multiple interactionsEXP 6480464CTD[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein]; Gentamicins results in increased expression of and results in increased secretion of HAVCR1 protein; Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of HAVCR1 mRNA]; Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of HAVCR1 protein]PMID:19349640 PMID:23335628 PMID:26779593
Havcr1increases expressionISOHAVCR1 (Homo sapiens)6480464CTDGentamicins results in increased expression of HAVCR1 mRNAPMID:29992668
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