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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886 Species: Rattus norvegicus RGD Object: Gene Symbol: Il10 Name: interleukin 10

Acc ID: CHEBI:17823 Term: calcitriol Definition: A hydroxycalciol that has formula C27H44O3. CasRN: 32222-06-3 Chemical ID: MESH:D002117

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:735591	6480464	CTD	Calcitriol results in increased expression of IL10 mRNA	PMID:16322758
increases expression	EXP		6480464	CTD	Calcitriol results in increased expression of IL10 protein	PMID:11679963