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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2933
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Acc ID: CHEBI:17775
Term: 7,9-dihydro-1H-purine-2,6,8(3H)-trione
Definition: An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Chemical ID: MESH:D014527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itpr1multiple interactionsISOITPR1 (Homo sapiens)6480464CTDUric Acid inhibits the reaction [Ethanol results in increased expression of and affects the localization of ITPR1 protein]PMID:17241155
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