GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730977
Species: Mus musculus
RGD Object: Gene
Symbol: Cdc42
Name: cell division cycle 42
Acc ID: CHEBI:17688
Term: (S)-nicotine
Definition: An optically active form of nicotine having S-configuration.
CasRN: 54-11-5
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of CDC42 mRNA

Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CDC42 mRNA]

PMID:20230807
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