GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Shc1 | increases expression | ISO | SHC1 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of SHC1; Glucose results in increased expression of SHC1 mRNA; Glucose results in increased expression of SHC1 protein | PMID:21778425 PMID:23993977 | Shc1 | multiple interactions | ISO | SHC1 (Homo sapiens) | 6480464 | CTD | SIRT1 inhibits the reaction [Glucose results in increased expression of SHC1]; SIRT1 mutant form promotes the reaction [Glucose results in increased expression of SHC1 mRNA]; SIRT1 mutant form promotes the reaction [Glucose results in increased expression of SHC1 protein]; SIRT1 protein inhibits the reaction [Glucose results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Glucose results in increased expression of SHC1 protein] | PMID:21778425 PMID:23993977 | | ||||||||||||||||||||||
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