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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2451
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cycs
Name: cytochrome c, somatic
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cycsaffects localizationEXP 6480464CTDGlucose affects the localization of CYCS proteinPMID:23192364
Cycsmultiple interactionsEXP 6480464CTDnaringenin inhibits the reaction [Glucose affects the localization of CYCS protein]PMID:23192364
Cycsincreases expressionISOCYCS (Homo sapiens)6480464CTDGlucose results in increased expression of CYCS mRNA; Glucose results in increased expression of CYCS proteinPMID:31115753 PMID:33962019
Cycsmultiple interactionsISOCYCS (Homo sapiens)6480464CTD[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA; diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA]; MitoTEMPO inhibits the reaction [Glucose results in increased expression of CYCS protein]PMID:31115753 PMID:33962019
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