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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732740 Species: Homo sapiens RGD Object: Gene Symbol: CAT Name: catalase

Acc ID: CHEBI:17620 Term: ferulic acid Definition: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. CasRN: 1135-24-6 Chemical ID: MESH:C004999

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases activity	ISO	RGD:737448	6480464	CTD	ferulic acid results in increased activity of CAT protein	PMID:20573577
multiple interactions	ISO	RGD:2279	6480464	CTD	ferulic acid inhibits the reaction [Fatty Acids, Unsaturated results in decreased activity of CAT protein] ferulic acid inhibits the reaction [[Fatty Acids, Unsaturated co-treated with Ethanol] results in decreased activity of CAT protein] ferulic acid inhibits the reaction [Ethanol results in decreased activity of CAT protein]	PMID:15381826