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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459 Species: Rattus norvegicus RGD Object: Gene Symbol: Cyp1a2 Name: cytochrome P450, family 1, subfamily a, polypeptide 2

Acc ID: CHEBI:17574 Term: biochanin A Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy groups at position 5 and a methoxy group at position 4'. CasRN: 491-80-5 Chemical ID: MESH:C004541

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases metabolic processing	ISO	RGD:735711	6480464	CTD	CYP1A2 protein results in increased metabolism of biochanin A	PMID:12814970