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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619569 Species: Homo sapiens RGD Object: Gene Symbol: ABCC2 Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Acc ID: CHEBI:17356 Term: 2-acetamidofluorene Definition: An ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2. CasRN: 53-96-3 Chemical ID: MESH:D015073

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	2-Acetylaminofluorene results in increased expression of ABCC2 mRNA	PMID:16426233 PMID:10691972
increases expression	EXP		6480464	CTD	2-Acetylaminofluorene results in increased expression of ABCC2 protein	PMID:10691972
increases expression	ISO	RGD:10368	6480464	CTD	2-Acetylaminofluorene results in increased expression of ABCC2 mRNA	PMID:16381673 PMID:16426233
multiple interactions	ISO	RGD:10368	6480464	CTD	NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]	PMID:16381673
increases expression	EXP		6480464	CTD	2-Acetylaminofluorene results in increased expression of ABCC2 mRNA	PMID:10691972 PMID:16426233
increases expression	ISO	RGD:10368	6480464	CTD	2-Acetylaminofluorene results in increased expression of ABCC2 mRNA	PMID:16426233 PMID:16381673