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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68469 Species: Mus musculus RGD Object: Gene Symbol: Por Name: P450 (cytochrome) oxidoreductase

Acc ID: CHEBI:17347 Term: testosterone Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. CasRN: 58-22-0 Chemical ID: MESH:D013739

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:68335	6480464	CTD	Testosterone inhibits the reaction [Dexamethasone results in increased expression of POR mRNA]	PMID:20032058
affects metabolic processing	EXP		6480464	CTD	POR protein affects the metabolism of Testosterone	PMID:15328377