GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr5a2 | increases expression | EXP | | 6480464 | CTD | Testosterone results in increased expression of NR5A2 mRNA | PMID:21273442 | Nr5a2 | multiple interactions | EXP | | 6480464 | CTD | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of NR5A2 mRNA; AR mutant form inhibits the reaction [Testosterone results in increased expression of NR5A2 mRNA]; NR5A2 mutant form inhibits the reaction [Testosterone results in increased expression of CYP19A1 mRNA]; Testosterone promotes the reaction [NR5A2 protein binds to CYP19A1 promoter] | PMID:21273442 PMID:32741896 | |
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