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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3094
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c2affects bindingISONR3C2 (Homo sapiens)6480464CTDTestosterone binds to NR3C2 proteinPMID:17105867
Nr3c2multiple interactionsISONR3C2 (Homo sapiens)6480464CTDTestosterone inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]PMID:17105867
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