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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732416 Species: Homo sapiens RGD Object: Gene Symbol: RPE65 Name: retinal pigment epithelium-specific protein 65kDa

Acc ID: CHEBI:17336 Term: all-trans-retinol Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry. CasRN: 11103-57-4 Chemical ID: MESH:D014801

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases chemical synthesis	EXP		6480464	CTD	RPE65 protein results in increased chemical synthesis of Vitamin A	PMID:16150724
increases metabolic processing	EXP		6480464	CTD	RPE65 protein results in increased metabolism of Vitamin A	PMID:16828753