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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3610
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rxraincreases expressionEXP 6480464CTDVitamin A results in increased expression of RXRA mRNAPMID:16180333
Rxraincreases expressionISORXRA (Homo sapiens)6480464CTDVitamin A results in increased expression of RXRA proteinPMID:17219422
Rxramultiple interactionsISORXRA (Homo sapiens)6480464CTD[Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNAPMID:17244623
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