GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fos | affects expression | EXP | | 6480464 | CTD | Morphine affects the expression of FOS mRNA | PMID:10521585 | Fos | increases expression | EXP | | 6480464 | CTD | Morphine results in increased expression of FOS mRNA; Morphine results in increased expression of FOS protein | PMID:12821175 PMID:15183518 PMID:22258905 PMID:32319158 | Fos | multiple interactions | EXP | | 6480464 | CTD | 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [[Morphine co-treated with Naloxone] results in increased expression of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Morphine results in increased expression of FOS protein]; [Morphine co-treated with Cocaine] affects the expression of FOS; [Morphine co-treated with N-Methyl-3,4-methylenedioxyamphetamine] affects the expression of FOS; [Morphine co-treated with Naloxone] results in increased expression of FOS protein; [Naloxone co-treated with Morphine] results in increased expression of FOS protein; [SCH772984 co-treated with bilobalide] inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; bilobalide inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; Genistein inhibits the reaction [Morphine results in increased expression of FOS protein]; Morphine affects the reaction [Formaldehyde results in increased expression of FOS protein]; N-(5-(3-dimethylaminobenzamido)-2-methylphenyl)-4-hydroxybenzamide inhibits the reaction [Morphine results in increased expression of FOS protein]; Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]; SCH772984 inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; U 0126 inhibits the reaction [Morphine results in increased expression of FOS protein] | PMID:10814832 PMID:16935424 PMID:20727678 PMID:22258905 PMID:22590628 PMID:25308750 PMID:32319158 | Fos | affects expression | ISO | Fos (Mus musculus) | 6480464 | CTD | Morphine deficiency affects the expression of FOS protein | PMID:27126842 | Fos | increases expression | ISO | Fos (Mus musculus) | 6480464 | CTD | Morphine results in increased expression of FOS protein | PMID:12934646 | Fos | increases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | Morphine results in increased expression of FOS protein | PMID:22258905 | Fos | multiple interactions | ISO | Fos (Mus musculus) | 6480464 | CTD | [Morphine co-treated with Dehydroepiandrosterone Sulfate] results in decreased expression of FOS protein; [Morphine co-treated with Dizocilpine Maleate] inhibits the reaction [Naloxone results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Morphine results in increased expression of FOS protein] | PMID:12934646 PMID:15196791 PMID:15196794 | | ||||||||||||||||||||||
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