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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564397 Species: Rattus norvegicus RGD Object: Gene Symbol: Hs6st2 Name: heparan sulfate 6-O-sulfotransferase 2

Acc ID: CHEBI:17303 Term: morphine Definition: A highly potent opiate analgesic psychoactive drug, morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly. CasRN: 57-27-2 Chemical ID: MESH:D009020

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1557635	6480464	CTD	Morphine results in increased expression of HS6ST2 mRNA	PMID:21178816