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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62028
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr0b1
Name: nuclear receptor subfamily 0, group B, member 1
Acc ID: CHEBI:17243
Term: mono(2-ethylhexyl) phthalate
Definition: The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C016599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr0b1decreases expressionEXP 6480464CTDmono-(2-ethylhexyl)phthalate results in decreased expression of NR0B1 mRNAPMID:16809437
Nr0b1increases expressionEXP 6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of NR0B1 mRNAPMID:16809437 PMID:30476341
Nr0b1multiple interactionsEXP 6480464CTDmono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of NR0B1 mRNA]PMID:30476341
Nr0b1multiple interactionsISONr0b1 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NR0B1 mRNAPMID:36189433
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