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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61882
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr4a3
Name: nuclear receptor subfamily 4, group A, member 3
Acc ID: CHEBI:17243
Term: mono(2-ethylhexyl) phthalate
Definition: The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C016599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr4a3increases expressionISONR4A3 (Homo sapiens)6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of NR4A3 mRNAPMID:19822197
Nr4a3increases expressionISONr4a3 (Mus musculus)6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of NR4A3 mRNAPMID:36189433
Nr4a3multiple interactionsISONr4a3 (Mus musculus)6480464CTD[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NR4A3 mRNAPMID:36189433
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