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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8increases activityEXP 6480464CTDGlucose results in increased activity of CASP8PMID:18791325
Casp8multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8]PMID:18791325
Casp8increases activityISOCasp8 (Mus musculus)6480464CTDGlucose results in increased activity of CASP8 proteinPMID:18973755
Casp8multiple interactionsISOCASP8 (Homo sapiens)6480464CTD[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA]PMID:33962019
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