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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3033
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad4
Name: SMAD family member 4
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad4increases expressionEXP 6480464CTDGlucose results in increased expression of SMAD4 proteinPMID:31838053
Smad4multiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of SMAD4 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased expression of SMAD4 protein]; farrerol inhibits the reaction [Glucose results in increased expression of SMAD4 protein]; LY2109761 inhibits the reaction [Glucose results in increased expression of SMAD4 protein]PMID:31838053
Smad4increases expressionISOSMAD4 (Homo sapiens)6480464CTDGlucose results in increased expression of SMAD4 proteinPMID:21367880
Smad4multiple interactionsISOSMAD4 (Homo sapiens)6480464CTDisoangustone A inhibits the reaction [Glucose results in increased expression of SMAD4 protein]PMID:21367880
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